Shanghai, China
Business Type:
Manufacturer/Factory, Trading Company
Registered Capital:
30000000 RMB
Plant Area:
>2000 square meters
Management System Certification:
ISO 9001
Average Lead Time:
Peak season lead time: one month
Off season lead time: one month
OEM/ODM Service
Sample Available
Russian / Portuguese Speaker

Ampicillin, Principen, Alpen manufacturer / supplier in China, offering High Quality 99.9% Ampicillin for USP Ep Cep CAS 69-53-4, Disposable Medical Protective Clothing (coverall) Being Made of Non-Woven Gas-Permeable Membrane Material for Hospital (S/M/L/XL/XXL/XXXL), Manufacturer of Raw Material   Paracetamol  CAS 103-90-2 Wholesale Price and so on.

Diamond Member Since 2019
Audited Supplier
  • High Quality 99.9% Ampicillin for USP Ep Cep CAS 69-53-4
  • High Quality 99.9% Ampicillin for USP Ep Cep CAS 69-53-4
  • High Quality 99.9% Ampicillin for USP Ep Cep CAS 69-53-4
  • High Quality 99.9% Ampicillin for USP Ep Cep CAS 69-53-4
  • High Quality 99.9% Ampicillin for USP Ep Cep CAS 69-53-4
  • High Quality 99.9% Ampicillin for USP Ep Cep CAS 69-53-4

High Quality 99.9% Ampicillin for USP Ep Cep CAS 69-53-4

Min. Order / Reference FOB Price
1 kg US $11-13/ kg
Port: Shanghai, China
Production Capacity: 1000000 Kg/Year
Payment Terms: L/C, T/T, D/P, Western Union, Paypal, Money Gram
Function: Antibiotic and Antimicrobial Agents
Certification: GMP, Reach, FDA, USP Ep
Grade Standard: Medicine Grade
Type: Analysis reagent
State: Solid
Volatile: Not Volatile

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Basic Info.

Model NO.
Suitable for
Elderly, Children, Adult
China Sinopharm
Transport Package
25 Kg/Drum
25 KG/drum
HS Code
High Quality 99.9% Ampicillin for USP Ep Cep CAS 69-53-4
Ampicillin is an antibiotic used to prevent and treat a number of bacterial infections, such as respiratory tract infections, urinary tract infections, meningitis, salmonellosis, and endocarditis. It may also be used to prevent group B streptococcal infection in newborns. It is used by mouth, by injection into a muscle, or intravenously.Like all antibiotics, it is not useful for the treatment of viral infections.
Product Name:Ampicillin PowderTest:HPLC
CAS:7177-48-2Active Ingredient:Ampicillin
Certificate:GMP ISO USP BpGrade Standard:Feed Grade, Food Grade, Medicine Grade
Type of Product:Auxiliaries and Other Medicinal ChemicalsShelf Life:2 Years Proper Storage
Transport Package:1kg Per Foil Bag, 10 Bags Per Carton. 25 Kg Per DrumSpecification99% min Tetramisole HCl


Ampicillin reacts with probenecid and methotrexate to decrease renal excretion. Large doses of ampicillin can increase the risk of bleeding with concurrent use of warfarin and other oral anticoagulants, possibly by inhibiting platelet aggregation. Ampicillin has been said to make oral contraceptives less effective,but this has been disputed. It can be made less effective by other antibiotic, such as chloramphenicol, erythromycin, cephalosporins, and tetracyclines. For example, tetracyclines inhibit protein synthesis in bacteria, reducing the target against which ampicillin acts. If given at the same time as aminoglycosides, it can bind to it and inactivate it. When administered separately, aminoglycosides and ampicillin can potentiate each other instead.Ampicillin causes skin rashes more often when given with allopurinol.Both the live cholera vaccine and live typhoid vaccine can be made ineffective if given with ampicillin. Ampicillin is normally used to treat cholera and typhoid fever, lowering the immunological response that the body has to mount.

Mechanism of action

The amino group (highlighted in magenta) is present on ampicillin but not penicillin G.Ampicillin is in the penicillin group of beta-lactam antibiotics and is part of the aminopenicillin family. It is roughly equivalent to amoxicillin in terms of activity. Ampicillin is able to penetrate Gram-positive and some Gram-negative bacteria. It differs from penicillin G, or benzylpenicillin, only by the presence of an amino group. This amino group, present on both ampicillin and amoxicillin, helps these antibiotics pass through the pores of the outer membrane of Gram-negative bacteria, such as E. coliProteus mirabilisSalmonella enterica, and Shigella.Ampicillin acts as an irreversible inhibitor of the enzyme transpeptidase, which is needed by bacteria to make the cell wall. It inhibits the third and final stage of bacterial cell wall synthesis in binary fission, which ultimately leads to cell lysis; therefore, ampicillin is usually bacteriolytic.


Ampicillin is well-absorbed from the GI tract (though food reduces its absorption), and reaches peak concentrations in one to two hours. The bioavailability is around 62% for parenteral routes. Unlike other penicillins, which usually have bind 60-90% to plasma proteins, ampicillin binds to only 15-20%.

Ampicillin is distributed through most tissues, though it is concentrated in the liver and kidneys. It can also be found in the cerebrospinal fluidwhen the meninges become inflamed (such as, for example, meningitis). Some ampicillin is metabolized by hydrolyzing the beta-lactam ring to penicilloic acid, though most of it is excreted unchanged. In the kidneys, it is filtered out mostly by tubular secretion; some also undergoes glomerular filtration, and the rest is excreted in the feces and bile.

Hetacillin and pivampicillin are ampicillin esters that have been developed to increase bioavailability.

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